SCHEMBL6835958

SCHEMBL6835958

Cc1cn([C@H]2CC(O)[C@@H](COC(=O)OCC(C)c3cc(Cl)ccc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835955 1.00 POLB (0.45) POLB
SCHEMBL13666504 1.00 POLB (0.45) POLB
SCHEMBL6830921 0.92 TYMS (0.49) POLB
SCHEMBL6830919 0.92 TYMS (0.49) POLB
SCHEMBL6834133 0.92 RNASE1 (0.45)
SCHEMBL6835969 0.91 POLB (0.45) POLB
SCHEMBL13666506 0.91 POLB (0.45) POLB
SCHEMBL13666505 0.91 POLB (0.45) POLB
SCHEMBL6833515 0.91 POLB (0.45) POLB
SCHEMBL6833513 0.91 POLB (0.45) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6750335-B2 NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES NIGU CHEMIE GMBH (DE) 2004-06-15 US disclosed