Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666505 | 1.00 | POLB (0.45) | POLBTYMS | |
| SCHEMBL6835970 | 1.00 | POLB (0.45) | POLBTYMS | |
| SCHEMBL7263516 | 0.94 | POLB (0.45) | POLBTYMS | |
| SCHEMBL6892652 | 0.94 | POLB (0.45) | POLBTYMS | |
| SCHEMBL13666503 | 0.94 | POLB (0.45) | POLBTYMS | |
| SCHEMBL6830921 | 0.92 | TYMS (0.49) | POLBTYMS | |
| SCHEMBL6830919 | 0.92 | TYMS (0.49) | POLBTYMS | |
| SCHEMBL6830885 | 0.92 | RNASE1 (0.45) | — | |
| SCHEMBL6833515 | 0.91 | POLB (0.45) | POLBTYMS | |
| SCHEMBL13666504 | 0.91 | POLB (0.45) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750335-B2 | NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES | NIGU CHEMIE GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1224198-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | NIGU CHEMIE GMBH (DE) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | XRN2, XPA, NSUN2 | POLB 47/4885TYMS 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.