Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697167 | 0.84 | TSHR (0.58) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL4179476 | 0.84 | TSHR (0.58) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL31152075 | 0.84 | TSHR (0.58) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL4198767 | 0.84 | TSHR (0.58) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL6835364 | 0.82 | SMN1; SMN2 (0.46) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| Water SCHEMBL9888402 | 0.82 | TP53 (0.56) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL28277740 | 0.81 | NPC1 (0.50) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL31231255 | 0.80 | SMN1; SMN2 (0.50) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1786549 | 0.79 | SMN1; SMN2 (0.52) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL29290201 | 0.79 | ADRB2 (0.49) | UTS2RSMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6752929-B1 | SEPARATING THE CIS AND THE TRANS DIASTEREOMERS OF THE 2',3'-DIDEOXY-5-FLUORO-3'THIOCYTADINE DERIVATIVE BY SIMULATED MOVING BED CHROMATOGRAPHY TO OBTAIN AT LEAST ONE OF THE DIASTEREOMERS | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2004-06-22 | — | — | US | disclosed |
| US-6541631-B1 | Forming a solution containing first and second enantiomer of cis-(5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathi olan-2-yl)methyl butanoate, separating first and second enantiomer by simulated moving bed chromatography | PHARMA-ECO LABORATORIES, INC. | 2003-04-01 | — | — | US | disclosed |
| EP-1180104-B1 | METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF | JOHNSON MATTHEY PHARMACEUTICAL (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1180104-A1 | METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF | Pharm-Eco Laboratories Inc. (US) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000071539-A1 | METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF | PHARM-ECO LABORATORIES INC. (US) | 2000-11-30 | — | — | WO | disclosed |