Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733391 | 0.82 | PNP (0.48) | PNP | |
| SCHEMBL216786 | 0.81 | PNP (0.47) | PNPHPRT1 | |
| SCHEMBL8717488 | 0.78 | PNP (0.44) | PNPHPRT1 | |
| SCHEMBL16038272 | 0.73 | HPRT1 (0.51) | PNPHPRT1 | |
| SCHEMBL9170794 | 0.73 | HPRT1 (0.51) | PNPHPRT1 | |
| SCHEMBL8921021 | 0.73 | PNP (0.41) | PNPHPRT1 | |
| SCHEMBL15545139 | 0.72 | PNP (0.48) | PNPHPRT1 | |
| SCHEMBL8397615 | 0.71 | PNP (0.54) | PNPHPRT1 | |
| SCHEMBL16020625 | 0.71 | HPRT1 (0.53) | PNPHPRT1 | |
| SCHEMBL669005 | 0.71 | PNP (0.59) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040068111-A1 | Unsaturated phosphonate derivatives of purines and pyrimidines | AVENTIS PHARMACEUTICALS INC. | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068111-A1 | Unsaturated phosphonate derivatives of purines and pyrimidines | TYMP, NUDT1, PNP | PNP 3/4885HPRT1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.