Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216786 | 0.91 | PNP (0.47) | PNPHPRT1 | |
| SCHEMBL15545139 | 0.81 | PNP (0.48) | PNPHPRT1 | |
| SCHEMBL8397615 | 0.80 | PNP (0.54) | PNPHPRT1 | |
| SCHEMBL6836079 | 0.78 | PNP (0.43) | PNPHPRT1 | |
| SCHEMBL5935062 | 0.76 | PNP (0.70) | PNPFGFR1FGFR2 | |
| SCHEMBL15743133 | 0.75 | PNP (0.59) | PNPFGFR1FGFR2 | |
| SCHEMBL2346356 | 0.75 | PNP (0.51) | PNPFGFR1FGFR2 | |
| SCHEMBL16038272 | 0.74 | HPRT1 (0.51) | PNPHPRT1 | |
| SCHEMBL9170794 | 0.74 | HPRT1 (0.51) | PNPHPRT1 | |
| SCHEMBL8196747 | 0.74 | PNP (0.58) | PNPFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854228-A | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-12-29 | — | — | US | disclosed |