Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.71 |
| ▸ | SHBG | P04278 | 5/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841497 | 1.00 | AR (0.71) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6836734 | 0.91 | AR (0.70) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL7699350 | 0.91 | AR (0.70) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL7699351 | 0.91 | AR (0.70) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6841437 | 0.91 | AR (0.70) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL17302821 | 0.88 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL5026470 | 0.88 | AR (0.72) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24103284 | 0.83 | AR (1.00) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL24103286 | 0.83 | AR (1.00) | ARSHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL223290 | 0.83 | AR (1.00) | ARSHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209853-A1 | Orally active 7.alpha.-alkyl androgens | AKZO NOBEL N.V. (NL) | 2004-10-21 | — | — | US | disclosed |
| US-6756366-B1 | 19-NORTESTOSTERONE DERIVATIVES; ORALLY ACTIVE; HIGH POTENCY | AKZO NOBEL N.V. (NL) | 2004-06-29 | — | — | US | disclosed |
| EP-1212345-B1 | ORALLY ACTIVE 7-ALPHA-ALKYL ANDROGENS | AKZO NOBEL NV (NL) | 2003-08-06 | — | — | EP | disclosed |
| EP-1212345-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | Akzo Nobel N.V. (NL) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000059920-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209853-A1 | Orally active 7.alpha.-alkyl androgens | NR5A1, AR, SHBG | AR 2/4885SHBG 3/4885SERPINA6 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.