Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 5/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803387 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL29802950 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL5695477 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL3395103 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL3399447 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL30876965 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL9471231 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL9972758 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL3814678 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 | |
| SCHEMBL11637530 | 0.77 | PPARG (0.63) | PPARGCYP11B1CYP11B2TNKSSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756403-B2 | 6-AMINOCHROMAN-2-YL CARBOXYLIC ACIDS AND ESTERS AS PLATELET AGGREGATION INHIBITORS; FROM PHENOL AND KETOGLUTARIC ACID; OR FROM 2-HYDROXYACETOPHENONE AND DIETHYLOXALATE; OR FROM NITROPHENOL AND DIETHYL ESTER OF MALEIC ACID | ELI LILLY AND COMPANY | 2004-06-29 | — | — | US | disclosed |
| US-4122200-A | 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-10-24 | — | — | US | disclosed |
| US-4097582-A | 6',2-(2'-Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-06-27 | — | — | US | disclosed |