Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340641 | 0.94 | S1PR1 (0.60) | S1PR1S1PR4S1PR5S1PR3GRIN2D | |
| SCHEMBL77257 | 0.94 | S1PR1 (0.60) | S1PR1S1PR4S1PR5S1PR3GRIN2D | |
| SCHEMBL8883356 | 0.90 | SIGMAR1 (0.62) | S1PR1S1PR4S1PR5S1PR3GRIN2D | |
| SCHEMBL5074115 | 0.86 | RAB9A (0.57) | S1PR1S1PR4S1PR5S1PR3TRPV1 | |
| SCHEMBL3023471 | 0.85 | POLB (0.56) | S1PR1S1PR4S1PR5S1PR3TRPV1 | |
| SCHEMBL5281907 | 0.84 | CYP4F2 (0.52) | S1PR1S1PR4S1PR5S1PR3GRIN2D | |
| SCHEMBL5031452 | 0.83 | SIGMAR1 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15946032 | 0.83 | HDAC3 (0.63) | HDAC4HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL9978978 | 0.83 | TRPV1 (0.62) | S1PR1S1PR4S1PR5S1PR3TRPV1 | |
| SCHEMBL27559352 | 0.83 | HDAC4 (0.52) | S1PR1S1PR4S1PR5S1PR3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018458-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-5223384-A | Multilayer; paper support, subbing and photosensitive layer | KONICA CORPORATION (JP) | 1993-06-29 | — | — | US | disclosed |