Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.34 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6836594 | 0.75 | BCHE (0.33) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL5853853 | 0.75 | CYP2C19 (0.43) | L3MBTL1CYP2C19LMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5854814 | 0.75 | CYP2C19 (0.43) | L3MBTL1CYP2C19LMNAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7210056 | 0.73 | GPR3 (0.32) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL5855381 | 0.72 | KMT2A (0.32) | BCHEACHEGAA | |
| Hydrochloric Acid SCHEMBL5853392 | 0.71 | POLB (0.40) | TSHRL3MBTL1LMNARECQLGAA | |
| Hydrochloric Acid SCHEMBL5855467 | 0.70 | KMT2A (0.36) | BCHEACHETSHRL3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL6916548 | 0.69 | GPR3 (0.40) | BCHEACHECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL5853472 | 0.68 | GAA (0.42) | L3MBTL1HTTLMNARECQLGAA | |
| Hydrochloric Acid SCHEMBL5855483 | 0.68 | HDAC3 (0.35) | L3MBTL1LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |