Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386124 | 0.80 | AKT1 (0.46) | SIGMAR1MAOBATMAKT1ALDH1A1 | |
| SCHEMBL11162654 | 0.79 | SIGMAR1 (0.51) | SIGMAR1MAOBATMAKT1ALDH1A1 | |
| SCHEMBL25082424 | 0.79 | ATM (0.44) | SIGMAR1MAOBATML3MBTL1AKT1 | |
| SCHEMBL6810670 | 0.79 | ELANE (0.43) | MAOBLMNAHTTNPSR1L3MBTL1 | |
| SCHEMBL11105397 | 0.78 | AKT1 (0.45) | SIGMAR1MAOBATMAKT1ALDH1A1 | |
| SCHEMBL28461980 | 0.78 | SIGMAR1 (0.50) | SIGMAR1MAOBATMLMNAHTT | |
| SCHEMBL9456096 | 0.75 | ATM (0.41) | SIGMAR1MAOBATMAKT1ALDH1A1 | |
| SCHEMBL11107182 | 0.75 | AKT1 (0.48) | SIGMAR1MAOBATML3MBTL1AKT1 | |
| SCHEMBL544297 | 0.75 | ALDH1A1 (0.60) | SIGMAR1MAOBATMALDH1A1MAPT | |
| SCHEMBL30065841 | 0.75 | ALDH1A1 (0.60) | SIGMAR1MAOBATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756432-B2 | POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-29 | — | — | US | disclosed |
| US-20030153655-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-14 | — | — | US | disclosed |
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |