Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055150 | 0.91 | HPGD (0.89) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL17744864 | 0.87 | MEN1 (0.66) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL3690383 | 0.86 | POLB (0.79) | POLBHPGDMAPTNPC1RAB9A | |
| N-O-Tolylbenzamide SCHEMBL3223289 | 0.85 | HPGD (1.00) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL6864568 | 0.85 | HPGD (0.67) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL1705539 | 0.84 | HDAC1 (0.61) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL6859613 | 0.84 | HPGD (0.77) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL2732354 | 0.84 | HPGD (0.77) | POLBHPGDMAPTNPC1RAB9A | |
| SCHEMBL17744841 | 0.84 | MAPT (0.65) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL6866826 | 0.84 | POLB (0.60) | POLBHPGDMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213572-A1 | 3-and 4-amino-N(alkyl phenyl) benzamide compounds and composition containing same as anticonvulsant drugs | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1987-03-11 | — | — | EP | claimed |
| EP-3628374-A2 | BCL-3 INHIBITORS | University College Cardiff Consultants Limited (GB) | 2020-04-01 | — | — | EP | disclosed |
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| WO-2010002779-A2 | NAPHTHYRIDININONES AS AURORA KINASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-01-07 | — | — | WO | disclosed |
| US-6808766-B1 | ALIGNMENT AGENT COMPRISING POLYURETHANE OR POLYUREA, USED IN ALIGNMENT OF LIQUID CRYSTAL MOLECULES THAT FORM LIQUID CRYSTAL ALIGNMENT FILM BY IRRADIATING THIN ALIGNMENT FILM FORMED ON SUBSTRATE WITH POLARIZED LIGHT OR ELECTRON RAYS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1111442-A1 | TREATING AGENT FOR LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DEVICE USING THE SAME, AND METHOD FOR ALIGNMENT OF LIQUID CRYSTAL | Nissan Chemical Industries, Ltd. (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5064862-A | 4-Amino-2*,6*-Dimethylbenzanilide | RESEARCH CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0213572-B1 | 3-AND 4-AMINO-N(ALKYL PHENYL) BENZAMIDE COMPOUNDS AND COMPOSITION CONTAINING SAME AS ANTICONVULSANT DRUGS | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0213572-A1 | 3-and 4-amino-N(alkyl phenyl) benzamide compounds and composition containing same as anticonvulsant drugs | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4638014-A | AMINOBENZANILIDES | RESEARCH CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | AURKA, AURKC, AURKB | POLB 435/4885HPGD 2277/4885MAPT 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.