Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 8/20 | 0.43 |
| ▸ | NEK2 | P51955 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883128 | 0.87 | FFAR1 (0.47) | TRPA1ARS1PR1S1PR5S1PR3 | |
| SCHEMBL3884459 | 0.83 | TRPA1 (0.51) | TRPA1ARS1PR1S1PR5S1PR3 | |
| SCHEMBL3686723 | 0.79 | FFAR4 (0.53) | ARFFAR1FFAR4 | |
| SCHEMBL3882141 | 0.79 | S1PR1 (0.45) | ARS1PR1S1PR5S1PR3FFAR4 | |
| SCHEMBL3882621 | 0.78 | FFAR4 (0.46) | TRPA1ARS1PR1S1PR5S1PR3 | |
| SCHEMBL3880966 | 0.77 | FFAR1 (0.45) | S1PR1S1PR5S1PR3FFAR1FFAR4 | |
| SCHEMBL3888350 | 0.76 | THRA (0.44) | ARS1PR1FFAR4 | |
| SCHEMBL3883636 | 0.76 | FFAR4 (0.46) | ARS1PR1S1PR5FFAR1FFAR4 | |
| SCHEMBL3883084 | 0.76 | FFAR4 (0.46) | TRPA1ARFFAR1FFAR4 | |
| SCHEMBL3884003 | 0.75 | TP53 (0.51) | ARFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2004-03-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | PTGER1, CYSLTR1, PTGS1 | TRPA1 135/4885AR 630/4885S1PR1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.