Acetoacetic Acid

Acetoacetic Acid

SCHEMBL6837513

CC(=O)CC(=O)O.CC(=O)CC(=O)O.CC(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
KDM6B O15054 1/20 0.46
KDM5C P41229 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46
PHF8 Q9UPP1 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
LDHA P00338 1/20 0.44
SRR Q9GZT4 1/20 0.44
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
LMNA P02545 2/20 0.41
SLC15A2 Q16348 1/20 0.41
TP53 P04637 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.36
HTT P42858 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL18911302 0.94 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL8760340 0.94 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL28987667 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL16401788 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5427882 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5158888 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL8751789 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL9278066 0.91 KDM4E (0.48) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL1406366 0.87 LDHA (0.57) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL1144213 0.87 LDHA (0.57) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6765056-B2 ALDEHYDE-FUNCTIONAL POLYURETHANE COMPRISING DISPERSING GROUPS, AND A LOW MOLECULAR WEIGHT ALDEHYDE-REACTIVE CROSSLINKER SELECTED FROM POLYAMINES AND CYANO, SULFO, KETO-, PHOSPHONO, OR NITRO-FUNCTIONAL COMPOUNDS; REFINISHING CARS AKZO NOBEL N.V. (NL) 2004-07-20 US disclosed
US-6753383-B2 REDUCING FREE ALDEHYDES IN DISPERSIONS, SUSPENSIONS, EMULSIONS AND SOLUTIONS BY SCAVENGING WITH A THIOAMINE COMPOUND; ODORLESS; NONTOXIC; DISCOLORATION INHIBITION; TEXTILES; GASES CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2004-06-22 US disclosed
EP-1216962-B1 Method for removing free aldehydes CONSORTIUM ELEKTROCHEM IND (DE) 2003-10-15 EP disclosed
EP-1307496-A1 AQUEOUS CROSS-LINKABLE BINDER COMPOSITION AND ITS USE IN THE PRODUCTION OF LACQUER COATINGS Akzo Nobel N.V. (NL) 2003-05-07 EP disclosed
EP-1216962-A1 Method for removing free aldehydes Consortium für elektrochemische Industrie GmbH (DE) 2002-06-26 EP disclosed
US-20020040093-A1 Aqueous cross-linkable binder composition and its use in the production of lacquer coatings AKZO NOBEL N. V. (NL) 2002-04-04 US disclosed
WO-2002014399-A1 AQUEOUS CROSS-LINKABLE BINDER COMPOSITION AND ITS USE IN THE PRODUCTION OF LACQUER COATINGS AKZO NOBEL N.V. (NL) 2002-02-21 WO disclosed
US-5084536-A Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOECHST AG (DE) 1992-01-28 US disclosed
US-4871822-A Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J HOECHST AG (DE) 1989-10-03 US disclosed