Acetoacetic Acid

Acetoacetic Acid

SCHEMBL8760340

CC(=O)CC(=O)O.CC(C)O.CC(C)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
KDM6B O15054 1/20 0.46
KDM5C P41229 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46
PHF8 Q9UPP1 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
LDHA P00338 1/20 0.44
SRR Q9GZT4 1/20 0.44
ALDH1A1 P00352 5/20 0.41
LMNA P02545 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
SLC15A2 Q16348 1/20 0.41
TP53 P04637 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.36
HTT P42858 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL18911302 1.00 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL28987667 0.97 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL16401788 0.97 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5158888 0.97 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL5427882 0.97 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL6837513 0.94 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL8751789 0.92 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL9278066 0.91 KDM4E (0.48) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL10615681 0.90 KDM4E (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL1406366 0.87 LDHA (0.57) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100439415-C Process for producing aliphatic polyester and aliphatic polyester MITSUBISHI CHEM CORP (JP) 2008-12-03 CN disclosed
CN-1875048-A Process for producing aliphatic polyester and aliphatic polyester MITSUBISHI CHEM CORP (JP) 2006-12-06 CN disclosed
EP-0775590-A1 Image recording paper containing silicone FUJI XEROX CO., LTD. (JP) 1997-05-28 EP disclosed