Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698266 | 0.83 | NPC1 (0.39) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL3687435 | 0.82 | PNMT (0.33) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL2505648 | 0.82 | PNMT (0.33) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL7195348 | 0.79 | SRD5A2 (0.36) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL27348144 | 0.78 | PNMT (0.45) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL28286932 | 0.77 | PNMT (0.44) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL28220071 | 0.77 | PNMT (0.44) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL6211217 | 0.77 | PNMT (0.33) | PNMT | |
| SCHEMBL9659755 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9APGRSRD5A2 | |
| SCHEMBL28762096 | 0.76 | PNMT (0.37) | PNMTNPC1RAB9APGRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753378-B2 | GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS | MITSUI CHEMICALS, INC. (JP) | 2004-06-22 | — | — | US | disclosed |