SCHEMBL3687435

SCHEMBL3687435

CC(C)[Zr]c1c(C2=CC=CC2)ccc2c1Cc1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PGR P06401 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698266 0.83 NPC1 (0.39) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL2505648 0.82 PNMT (0.33) PNMTNPC1RAB9APGRSRD5A2
SCHEMBL6837569 0.82 PNMT (0.33) PNMTNPC1RAB9APGRSRD5A2
SCHEMBL7195348 0.79 SRD5A2 (0.36) PNMTNPC1RAB9APGRSRD5A2
SCHEMBL27348144 0.78 PNMT (0.45) PNMTNPC1RAB9APGRSRD5A2
Hydrochloric Acid SCHEMBL2387757 0.78 PNMT (0.33) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL9278264 0.77 PNMT (0.34) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL9278339 0.77 PNMT (0.34) PNMTNPC1RAB9APGRCYP1A2
SCHEMBL28220071 0.77 PNMT (0.44) PNMTNPC1RAB9APGRSRD5A2
SCHEMBL28286932 0.77 PNMT (0.44) PNMTNPC1RAB9APGRSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1712350-B1 LAYERED PRODUCT OF THERMOPLASTIC OLEFIN ELASTOMER MITSUI CHEMICALS INC (JP) 2010-04-07 EP disclosed
EP-1712350-A1 LAYERED PRODUCT OF THERMOPLASTIC OLEFIN ELASTOMER Mitsui Chemicals, Inc. (JP) 2006-10-18 EP disclosed
US-6255425-B1 EXTRUDED ARTICLE FORMED BY EXTRUSION OF SYNDIOTACTIC PROPYLENE HOMOPOLYMER HAVING SYNDIOTACTIC PENTAD FRACTION OF AT LEAST 0.7 MITSUI CHEMICALS, INC. (JP) 2001-07-03 US disclosed
EP-0882076-B1 SUPPORTED CATALYST SYSTEM BASF AG (DE) 2001-04-25 EP disclosed
EP-0789096-B1 Polypropylene fibers FINA RESEARCH (BE) 2000-05-03 EP disclosed
US-5753762-A Polyporpylene fibers FINA RESEARCH, S.A. (BE) 1998-05-19 US disclosed
EP-0634505-B1 Improved propylene polymer yarn and articles made therefrom MONTELL NORTH AMERICA INC (US) 1998-01-07 EP disclosed
EP-0789096-A1 Polypropylene fibers FINA RESEARCH S.A. (BE) 1997-08-13 EP disclosed
US-5624621-A Process of making polyprophylene fibers MITSUI TOATSU CHEMICALS, INC. (JP) 1997-04-29 US disclosed
EP-0414047-B1 A novel polypropylene fiber and a preparation process thereof MITSUI TOATSU CHEMICALS (JP) 1997-01-08 EP disclosed
US-5212247-A POLYPROPYLENE RESIN COMPOSITIONS OF HIGH SYNDIOTACTICITY AND PREPARATION PROCESS THEREOF MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-18 US disclosed
EP-0412416-B1 A COPOLYMER OF PROPYLENE AND BUTENE MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
US-5196496-A Zirconium or hafnium catalysts HIMONT INCORPORATED (US) 1993-03-23 US disclosed
US-5169924-A Molding materials having chacteristic nuclear magnetic resonance absorption spectra, flexibility, strength, transparency MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-12-08 US disclosed
EP-0500944-A1 CATALYST FOR $g(a)-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-$g(a)-OLEFIN THEREWITH MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-02 EP disclosed
EP-0419681-A1 METHOD OF PRODUCING SYNDIOTACTIC POLYPROPYLENE MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-03 EP disclosed
EP-0414047-A2 A novel polypropylene fiber and a preparation process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-02-27 EP disclosed
EP-0412416-A1 A copolymer of propylene and butene MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-02-13 EP disclosed
EP-0405201-A2 Polypropylene resin compositions of high syndiotacticity and preparation process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-01-02 EP disclosed
EP-0395055-A1 Syndiotactic polypropylene copolymer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-31 EP disclosed