Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839051 | 0.98 | ADORA2A (0.72) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| SCHEMBL9727082 | 0.81 | DRD4 (0.64) | CHRNA7ALDH1A1RXFP1HSD17B10HPGD | |
| SCHEMBL14270763 | 0.79 | CHRNA7 (0.58) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| SCHEMBL5584871 | 0.79 | KMT2A (0.72) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| SCHEMBL6632198 | 0.79 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL11919745 | 0.79 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL6873071 | 0.79 | CHRNA7 (0.50) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| SCHEMBL6873079 | 0.79 | CHRNA7 (0.50) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| SCHEMBL7427719 | 0.78 | LMNA (0.68) | ADORA2AADORA1ADORA2BCHRNA7LMNA | |
| Hydrochloric Acid SCHEMBL2896612 | 0.78 | CHRNA7 (0.98) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |