SCHEMBL6838205

SCHEMBL6838205

Cc1cccc2c1nc(C(F)(F)F)c1nc(-c3ccccc3)n(CCC3CNCCO3)c12

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 7/20 0.40
SLC6A2 P23975 10/20 0.37
SLC6A4 P31645 9/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37
SLC6A3 Q01959 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6837755 0.90 SLC6A2 (0.38) SSTR4SLC6A2SLC6A4GRIN1GRIN2B
SCHEMBL6838666 0.88 SSTR4 (0.38) SSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL6837757 0.88 SSTR4 (0.38) SSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL6838056 0.87 SSTR4 (0.37) SSTR4SLC6A2SLC6A4GRIN1GRIN2B
SCHEMBL6838669 0.87 SSTR4 (0.37) SSTR4SLC6A2SLC6A4GRIN1GRIN2B
SCHEMBL6837707 0.86 MERTK (0.37) SLC6A4
SCHEMBL6840037 0.86 SSTR4 (0.36) SSTR4SLC6A2SLC6A4GRIN1GRIN2B
SCHEMBL6838736 0.85 SSTR4 (0.38) SSTR4SLC6A2SLC6A4SLC6A3
SCHEMBL6837682 0.85 GRIN1 (0.35) SLC6A2SLC6A4GRIN1GRIN2BSLC6A3
SCHEMBL6840155 0.84 SSTR4 (0.38) SSTR4SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040054182-A1 1h-imidazopyridine derivatives HOKURIKU SEIYAKU CO., LTD. (JP) 2004-03-18 US disclosed
EP-1256582-A1 1H-IMIDAZOPYRIDINE DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2002-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040054182-A1 1h-imidazopyridine derivatives IL2, IL1A, IL4 SSTR4 963/4885SLC6A2 4336/4885SLC6A4 3973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.