Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281008 | 0.88 | HTT (0.53) | HTTTHRBGAAALDH1A1TDP1 | |
| SCHEMBL3635788 | 0.79 | CD44 (0.43) | HTTGAAALDH1A1CD44CYP3A4 | |
| SCHEMBL6834041 | 0.77 | HTT (0.42) | HTTTHRBGAAALDH1A1CD44 | |
| SCHEMBL6840595 | 0.77 | HTT (0.46) | HTTTHRBGAAALDH1A1CD44 | |
| SCHEMBL7138488 | 0.76 | KAT2B (0.47) | HTTALDH1A1CD44CYP3A4TDP1 | |
| SCHEMBL13497804 | 0.74 | CD44 (0.46) | HTTGAAALDH1A1CD44CYP3A4 | |
| SCHEMBL11575405 | 0.72 | HTT (0.49) | HTTTHRBGAAALDH1A1CYP3A4 | |
| SCHEMBL29691338 | 0.72 | HTT (0.49) | HTTTHRBGAAALDH1A1CYP3A4 | |
| SCHEMBL23908718 | 0.72 | GAA (0.40) | HTTTHRBGAAALDH1A1TDP1 | |
| SCHEMBL2228032 | 0.72 | HTT (0.67) | HTTTHRBGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759503-B2 | CYANOETHYLATED TOLUENEDIAMINES (CNTDAS), PROCESSES FOR SYNTHESIZING THEM, AND COMPOSITIONS CONTAINING THEM THE CNTDAS ARE PARTICULARLY SUITABLE FOR USE AS LATENT CURING AGENTS FOR EPOXY RESINS. | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-06 | — | — | US | claimed |
| US-20030144540-A1 | N-cyanoethylated ortho and meta toluenediamine compositions and process for making them | STARNER WILLIAM EDWARD (US) | 2003-07-31 | — | — | US | claimed |
| US-6593487-B1 | Latent curing agents for epoxy resins | AIR PRODUCTS AND CHEMICALS, INC. | 2003-07-15 | — | — | US | claimed |
| EP-1321459-A2 | N-Cyanoethylated ortho and meta toluenediamine compositions and process for making them | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2003-06-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144540-A1 | N-cyanoethylated ortho and meta toluenediamine compositions and process for making them | DNMT1, PNMT, TET1 | HTT 2214/4885THRB 2814/4885GAA 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.