SCHEMBL68385

SCHEMBL68385

O=C(NCc1ncc(Br)cc1Cl)c1c(Cl)ccnc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK10 P53779 1/20 0.34
KDR P35968 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
PTGES O14684 1/20 0.33
P2RX7 Q99572 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4614052 0.94 KMT2A (0.39) POLBKMT2AMEN1CTDSP1ALDH1A1
SCHEMBL319697 0.89 KMT2A (0.41) POLBKMT2AMEN1CTDSP1SMN1; SMN2
SCHEMBL4614047 0.88 CNR2 (0.35) POLBALDH1A1SMN1; SMN2HPGDLMNA
SCHEMBL6030405 0.87 P2RX7 (0.43) POLBKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL6480960 0.85 POLB (0.40) POLBKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL6031065 0.82 KMT2A (0.51) KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A
SCHEMBL6030456 0.81 MEN1 (0.39) POLBKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL16793840 0.80 NPC1 (0.39) KMT2AMEN1CTDSP1ALDH1A1SMN1; SMN2
SCHEMBL5565736 0.80 POLB (0.42) POLBKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL6901764 0.76 P2RX7 (0.40) POLBKMT2AMEN1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2798 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
CN-108184905-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-12-28 CN claimed
CN-107996613-B Compositions comprising biological control agents and pesticides 拜尔农作物科学股份公司 2021-10-22 CN claimed
CN-109169661-B Compositions comprising biological control agents and insecticides 拜耳作物科学股份公司 2021-09-21 CN claimed
CN-107926985-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-02-02 CN claimed
EP-3488700-B1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE BAYER CROPSCIENCE AG (DE) 2020-12-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
EP-2854545-B1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2020-10-21 EP claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
CN-106962403-B Compositions comprising biological control agents and pesticides 拜耳作物科学股份公司 2020-05-05 CN claimed
WO-2008071672-A2 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-06-19 WO claimed
EP-1931200-A1 FUNGICIDE COMPOSITION COMPRISING AN ARYLAMIDINE DERIVATIVE AND TWO KNOWN FUNGICIDE COMPOUNDS Bayer CropScience AG (DE) 2008-06-18 EP claimed
WO-2008046856-A2 FUNGICIDAL COMPOSITIONS BASF SE (DE) 2008-04-24 WO claimed
EP-1898709-A1 FUNGICIDE COMPOSITION COMPRISING A PHOSPHOROUS ACID DERIVATIVE, A MANDELAMIDE TYPE COMPOUND AND A FURTHER FUNGICIDE COMPOUND Bayer CropScience S.A. (FR) 2008-03-19 EP claimed
WO-2007031507-A1 FUNGICIDE COMPOSITION COMPRISING AN ARYLAMIDINE DERIVATIVE AND TWO KNOWN FUNGICIDE COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-03-22 WO claimed
WO-2006136551-A1 FUNGICIDE COMPOSITION COMPRISING A PHOSPHOROUS ACID DERIVATIVE, A MANDELAMIDE TYPE COMPOUND AND A FURTHER FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2006-12-28 WO claimed
US-7074742-B2 Pyridinyl amides and imides for use as fungicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-07-11 US claimed
US-20040044040-A1 Pyridinyl amides and imides for use as fungicides E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-04 US claimed
EP-1322614-A2 PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES E. I. du Pont de Nemours and Company (US) 2003-07-02 EP claimed
WO-2002022583-A2 PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-03-21 WO claimed