Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030405 | 0.88 | P2RX7 (0.43) | P2RX7KMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL319697 | 0.88 | KMT2A (0.41) | P2RX7MAOBKMT2APOLBNPC1 | |
| SCHEMBL6888143 | 0.87 | POLB (0.46) | P2RX7MAOBKMT2APOLBNPC1 | |
| SCHEMBL4614052 | 0.83 | KMT2A (0.39) | P2RX7KMT2APOLBNPC1RAB9A | |
| SCHEMBL6905404 | 0.81 | TAAR1 (0.43) | P2RX7KMT2APOLBNPC1RAB9A | |
| SCHEMBL3430687 | 0.81 | LMNA (0.42) | P2RX7MAOBKMT2ANPC1RAB9A | |
| SCHEMBL6480960 | 0.76 | POLB (0.40) | P2RX7KMT2APOLBNPC1SMN1; SMN2 | |
| SCHEMBL68385 | 0.76 | POLB (0.40) | P2RX7KMT2APOLBNPC1RAB9A | |
| SCHEMBL3430049 | 0.75 | P2RX7 (0.48) | P2RX7KMT2APOLBNPC1RAB9A | |
| SCHEMBL28048682 | 0.74 | POLB (0.52) | MAOBPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322614-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-02 | — | — | EP | claimed |
| WO-2002022583-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-21 | — | — | WO | claimed |
| EP-1485355-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |