Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833709 | 0.91 | HRH1 (0.36) | KCNH2HRH1HRH4HRH3ADORA2A | |
| SCHEMBL6838072 | 0.91 | HRH1 (0.35) | KCNH2HRH1HRH4HRH3ADORA2A | |
| SCHEMBL6840136 | 0.87 | CCR3 (0.33) | KCNH2HRH1HRH4HRH3MAPT | |
| SCHEMBL6833702 | 0.86 | SLC6A2 (0.39) | KCNH2SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL6838102 | 0.83 | SLC6A2 (0.37) | KCNH2SLC6A2SLC6A4SLC6A3TDO2 | |
| SCHEMBL6838640 | 0.83 | KCNH2 (0.37) | KCNH2SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL6838620 | 0.83 | SLC6A2 (0.38) | KCNH2SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL6838013 | 0.82 | ADORA2A (0.35) | ADORA2AHSD17B10CASR | |
| SCHEMBL6840144 | 0.81 | SLC6A2 (0.37) | KCNH2SLC6A2SLC6A4SLC6A3TDO2 | |
| SCHEMBL6837688 | 0.80 | SLC6A2 (0.36) | KCNH2SLC6A2SLC6A4SLC6A3TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | KCNH2 383/4885SLC6A2 4336/4885SLC6A4 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.