Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383463 | 0.80 | L3MBTL1 (0.59) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL9789608 | 0.79 | L3MBTL1 (0.58) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL11664767 | 0.75 | GAA (0.46) | MEN1KMT2AKAT2BPTGS1PTGS2 | |
| SCHEMBL11498746 | 0.75 | MEN1 (0.47) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL11782320 | 0.74 | L3MBTL1 (0.61) | MEN1KMT2AKAT2BL3MBTL1ALDH1A1 | |
| SCHEMBL8662859 | 0.73 | GPR84 (0.49) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL11658039 | 0.73 | MEN1 (0.43) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL23398798 | 0.73 | MEN1 (0.55) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL11500425 | 0.73 | SMN1; SMN2 (0.54) | MEN1KMT2AKAT2BL3MBTL1PTGS1 | |
| SCHEMBL1944581 | 0.72 | TSHR (0.49) | MEN1KMT2AALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281143-A | Process for preparing 1-aryl-3-amino-5-pyrazolones | EASTMAN KODAK COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| US-4642283-A | USING A BASIC COMPOUND IN THE DEVELOPER TO EFFECT COUPLING OF AN O-QUINONEDIAZIDE COMPOUND IN THE NONEXPOSED AREA | FUJI PHOTO FILM CO., LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0154980-A1 | Negative working light-sensitive lithographic plate requiring no dampening solution and plate making process | FUJI PHOTO FILM CO., LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| US-4281143-A | Process for preparing 1-aryl-3-amino-5-pyrazolones | EASTMAN KODAK COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4281143-A | Process for preparing 1-aryl-3-amino-5-pyrazolones | EASTMAN KODAK COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4281143-A | Process for preparing 1-aryl-3-amino-5-pyrazolones | EASTMAN KODAK COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4076943-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-28 | — | — | US | disclosed |
| US-4061653-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-3950528-A | HYPOTENSIVE AGENTS, SALURETICS, DIURETICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |