SCHEMBL6838982

SCHEMBL6838982

OCCOc1cccc(/C=C/c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 7/20 0.40
CYSLTR1 Q9Y271 7/20 0.40
SYK P43405 2/20 0.37
ALDH1A1 P00352 3/20 0.37
RECQL P46063 1/20 0.37
LCK P06239 1/20 0.36
TLR4 O00206 3/20 0.36
TLR2 O60603 3/20 0.36
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FURIN P09958 1/20 0.35
PKM P14618 1/20 0.34
TUBB1 Q9H4B7 1/20 0.34
CHRNA7 P36544 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838983 1.00 CYSLTR2 (0.40) CYSLTR2CYSLTR1SYKALDH1A1RECQL
SCHEMBL8990592 0.89 CYSLTR2 (0.42) CYSLTR2CYSLTR1SYKALDH1A1RECQL
SCHEMBL3430942 0.89 CYSLTR2 (0.39) CYSLTR2CYSLTR1ALDH1A1LCKTLR4
SCHEMBL8021069 0.84 PPARA (0.38) ALDH1A1RECQLSMN1; SMN2TUBB1CHRNA7
SCHEMBL195709 0.84 PPARA (0.38) ALDH1A1RECQLSMN1; SMN2TUBB1CHRNA7
SCHEMBL1130906 0.80 RELA (0.54) TUBB1
SCHEMBL20450511 0.80 RELA (0.54) TUBB1
SCHEMBL8653188 0.78 LCK (0.51) CYSLTR2CYSLTR1LCKMAOAMAOB
SCHEMBL8083921 0.78 PPARA (0.40) TUBB1CHRNA7
SCHEMBL8083916 0.78 PPARA (0.40) TUBB1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6737204-B2 COMBINES A DIGITAL COLOR IMAGE WITH THE VERSATILITY OF AN ANALOG IMAGING METHOD TO CREATE A HYBRID DIGITAL/ANALOG IMAGE, WHEREIN AN ANALOG IMAGE IS FORMED DIRECTLY ON A DIGITALLY GENERATED IMAGE. KODAK POLYCHROME GRAPHICS, LLC 2004-05-18 US disclosed
WO-2003021215-A9 HYBRID PROOFING METHOD KODAK POLYCHROME GRAPHICS LLC (US) 2004-04-29 WO disclosed
US-20030068569-A1 Hybrid proofing method FPC INC. 2003-04-10 US disclosed
US-6194123-B1 Manufacturing method for color proofing elements MINNESOTA MINING AND MANUFACTURING COMPANY 2001-02-27 US disclosed
EP-0985165-A1 IONIC HALOMETHYL-1,3,5-TRIAZINE PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-03-15 EP disclosed
EP-0983532-A1 AQUEOUS DEVELOPABLE COLOR PROOFING ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-03-08 EP disclosed
US-6010821-A CONTAINING A WATER SOLUBLE OR DISPERSIBLE TRIAZINE PHOTOINITIATOR MINNESOTA MINING AND MANUFACTURING COMPANY 2000-01-04 US disclosed
WO-1998053368-A1 AQUEOUS DEVELOPABLE COLOR PROOFING ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-11-26 WO disclosed
WO-1998053369-A1 IONIC HALOMETHYL-1,3,5-TRIAZINE PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-11-26 WO disclosed
EP-0529896-B1 Light-sensitive article containing migration-resistant halomethyl-1,3,5-triazine photoinitiator MINNESOTA MINING & MFG (US) 1998-04-22 EP disclosed
EP-0529789-B1 Negative single sheet color proofing system based on aqueous developable photo-oligomers MINNESOTA MINING & MFG (US) 1997-08-27 EP disclosed
EP-0772089-A2 Low optical dot gain color proof composites MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-05-07 EP disclosed
EP-0740208-A1 Aqueous developable color proofing elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-30 EP disclosed
US-5484919-A Migration-resistant halomethyl-1,3,5-triazine photoinitiator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-16 US disclosed
US-5298361-A Chromophore substituted halomethyl-1,3,5-triazine photopolymerization initiator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-29 US disclosed
US-5258261-A With water insoluble polymeic particles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-02 US disclosed
US-5248583-A Multilayer light sensitive element with carriers, release layers as oxygen barriers, photopolymerizable layers and thermal adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-28 US disclosed
EP-0530962-A1 Anti-blocking, water soluble top coat for color proofing films MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-10 EP disclosed
EP-0529896-A1 Light-sensitive article containing migration-resistant halomethyl-1,3,5-triazine photoinitiator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-03 EP disclosed
EP-0529789-A1 Negative single sheet color proofing system based on aqueous developable photo-oligomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-03 EP disclosed