Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705112 | 0.90 | NR3C1 (0.47) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL10530695 | 0.88 | NR3C1 (0.55) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL4978346 | 0.85 | NR3C1 (0.61) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL4978357 | 0.85 | NR3C1 (0.61) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL6706204 | 0.80 | NR3C1 (0.42) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL28472478 | 0.78 | NR3C1 (0.42) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL7795449 | 0.75 | SHBG (0.48) | PGRNR3C1ARCYP19A1TDP1 | |
| SCHEMBL10723544 | 0.75 | NR3C1 (0.45) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL6167275 | 0.74 | NR3C1 (0.42) | PGRNR3C1ARNR3C2CYP19A1 | |
| SCHEMBL4255035 | 0.74 | NR3C1 (0.44) | PGRNR3C1ARNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759399-B1 | USING SUCH AS GAMMA-LACTONE OF 10-ETHYNYL-17-HYDROXY-3-OXO-19-NOR-17-PREGNA-4,9(11)-DIENE-21-CARBOXYLIC ACID | AVENTIS PHARMA S.A. (FR) | 2004-07-06 | — | — | US | claimed |