Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29148471 | 1.00 | TDP1 (0.49) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| SCHEMBL26464914 | 1.00 | TDP1 (0.49) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| SCHEMBL27876571 | 1.00 | TDP1 (0.49) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL30900695 | 0.98 | TDP1 (0.47) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL28115938 | 0.98 | TDP1 (0.47) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| SCHEMBL15856910 | 0.98 | L3MBTL1 (0.50) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL28902719 | 0.96 | TDP1 (0.46) | TDP1L3MBTL1KCNH2NOS3NOS1 | |
| SCHEMBL8582607 | 0.92 | L3MBTL1 (0.43) | TDP1L3MBTL1NOS3NOS1NOS2 | |
| Ammonia Solution, Strong SCHEMBL28841614 | 0.91 | L3MBTL1 (0.42) | TDP1L3MBTL1NOS3NOS1NOS2 | |
| Bromide SCHEMBL28285568 | 0.91 | L3MBTL1 (0.42) | TDP1L3MBTL1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759544-B2 | FOR USE IN THE ORAL HYGIENE | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20030023084-A1 | Antimicrobially active acesulfame complexes, process for their preparation and their use | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030023084-A1 | Antimicrobially active acesulfame complexes, process for their preparation and their use | ACE, AP1S1, AP1M1 | TDP1 3522/4885L3MBTL1 4669/4885KCNH2 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.