Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839279 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839284 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6838367 | 0.97 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6838370 | 0.97 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839222 | 0.95 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839223 | 0.95 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839214 | 0.91 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839212 | 0.91 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6839218 | 0.91 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6838377 | 0.82 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759101-B2 | USEFUL IN FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS; USE TO LOWER MELTING POINT OR LOWER FREEZING POINT, OF LIQUID CRYSTAL COMPOSITIONS | DISPLAYTECH, INC. | 2004-07-06 | — | — | US | disclosed |
| US-20020195585-A1 | Liquid crystalline materials containing perfluoroalkyl and alkenyl tail groups | CITIZEN FINEDEVICE CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020195585-A1 | Liquid crystalline materials containing perfluoroalkyl and alkenyl tail groups | ELOVL3, LPCAT1, FABP4 | NPC1 1442/4885RAB9A 3617/4885SMN1; SMN2 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.