Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187 | 0.90 | KDM4E (0.47) | KDM4ELMNAPIK3C3MAPK8ADORA2A | |
| Methane SCHEMBL27916786 | 0.89 | KDM4E (0.46) | KDM4ELMNAPIK3C3MAPK8ADORA2A | |
| SCHEMBL1827089 | 0.89 | KDM4E (0.46) | KDM4ELMNAPIK3C3MAPK8ADORA2A | |
| Cytosine SCHEMBL14125692 | 0.83 | TSHR (0.42) | XIAPBIRC2ADORA2AROCK2ADORA1 | |
| Cytosine SCHEMBL27595867 | 0.79 | TSHR (0.40) | XIAPBIRC2ADORA2AADORA1JAK2 | |
| Cytosine SCHEMBL4059 | 0.79 | — | — | |
| Cytosine SCHEMBL4657334 | 0.79 | DYRK1A (0.44) | ADORA2AADORA1MAPTAURKAJAK2 | |
| Cytosine SCHEMBL1330400 | 0.79 | — | — | |
| Cytosine SCHEMBL1330710 | 0.79 | — | — | |
| Cytosine SCHEMBL8910522 | 0.78 | TSHR (0.43) | ADORA2AADORA1JAK2CDK8CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831174-B2 | Nucleosides | SHIRE BIOCHEM INC. (CA) | 2004-12-14 | — | — | US | disclosed |
| EP-0674634-B1 | PROCESS FOR PREPARING SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 2003-04-16 | — | — | EP | disclosed |
| US-20010041797-A1 | Processes for preparing substituted 1, 3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2001-11-15 | — | — | US | disclosed |
| US-6175008-B1 | VIRICIDES FROM REACTION MERCAPTOALDEHYDE WITH ACETOESTER AND 1,4-DITHIANE-2,5-DIOL | BIOCHEM PHARMA INC. (CA) | 2001-01-16 | — | — | US | disclosed |
| US-5684164-A | CHEMICAL INTERMEDIATES | BIOCHEM PHARMA INC. (CA) | 1997-11-04 | — | — | US | disclosed |
| US-5466806-A | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041797-A1 | Processes for preparing substituted 1, 3-oxathiolanes with antiviral properties | TYMP, TYMS, PNP | KDM4E 3414/4885LMNA 2601/4885PIK3C3 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.