SCHEMBL21187

SCHEMBL21187

CC(=O)Nc1cc[nH]c(=O)n1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
LMNA P02545 1/20 0.47
PIK3C3 Q8NEB9 3/20 0.44
MAPK8 P45983 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
ROCK2 O75116 1/20 0.42
ADORA1 P30542 3/20 0.41
ADORA2A P29274 2/20 0.41
PTK2 Q05397 1/20 0.41
HTR1F P30939 1/20 0.40
MAPT P10636 1/20 0.39
ADORA3 P0DMS8 3/20 0.39
ADORA2B P29275 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1827089 0.98 KDM4E (0.46) KDM4ELMNAPIK3C3MAPK8L3MBTL1
Methane SCHEMBL27916786 0.98 KDM4E (0.46) KDM4ELMNAPIK3C3MAPK8L3MBTL1
Cytosine SCHEMBL6839375 0.90 KDM4E (0.41) KDM4ELMNAPIK3C3MAPK8L3MBTL1
Methylene Chloride SCHEMBL22285891 0.83 ADORA2A (0.35) KDM4ELMNAPIK3C3MAPK8HSP90AA1
SCHEMBL10679044 0.82 GRM5 (0.36) KDM4ELMNAADORA1ADORA2AMAOB
SCHEMBL28034702 0.81 ALDH1A1 (0.51) KDM4ELMNAPIK3C3ROCK2MAPT
SCHEMBL513900 0.81 CYP3A4 (0.38) KDM4EMAOBCYP1A2
SCHEMBL8709449 0.80 L3MBTL1 (0.46) KDM4ELMNAL3MBTL1ADORA1HTR1F
SCHEMBL1965199 0.80 ADORA3 (0.43) KDM4ELMNAADORA1ADORA2AMAPT
SCHEMBL1334904 0.80 ADORA3 (0.43) KDM4EADORA1ADORA2AHTR1FADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3477 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103936-A1 CHEMICALLY MODIFIED CIRCULAR RNA MOLECULE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海元码智药生物技术有限公司 2026-05-21 WO claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 CN claimed
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-12559515-B2 Cap compounds and RNAS comprising the same HELIX NANOTECHNOLOGIES INC (US) 2026-02-24 US claimed
EP-4684016-A2 METHODS AND MATERIALS FOR TREATING CANCER The Regents of the University of California (US) 2026-01-28 EP claimed
EP-4665850-A2 OLIGONUCLEOTIDES FOR MODULATING APOLIPOPROTEIN E (APOE) EXPRESSION AND METHODS OF USE THEREOF SciNeuro Therapeutics Inc. (US) 2025-12-24 EP claimed
EP-4606903-A1 METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEOSIDE CONTAINING PROTECTING GROUP, AND COMPOSITION Asymchem Life Science (Tianjin) Co., Ltd (CN) 2025-08-27 EP claimed
WO-2025137486-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC (US) 2025-06-26 WO claimed
US-20250206770-A1 CAP COMPOUNDS AND RNAS COMPRISING THE SAME HELIX NANOTECHNOLOGIES INC 2025-06-26 US claimed
CN-1566112-A Diastereoselective preparation method of lamivudine TRI LION PHARMACEUTICAL CO LTD (CN) 2005-01-19 CN claimed
WO-2004013182-A1 HYALURONIC ACID DERIVATIVES JASPER LTD LIABILITY CO. (US) 2004-02-12 WO claimed
US-20030089472-A1 For oxidation of lignin-containing materials (wood pulp) CODEXIS, INC. 2003-05-15 US claimed
WO-2003023134-A1 LACCASE ACTIVITY ENHANCERS FOR PULP BLEACHING CODEXIS INC (US) 2003-03-20 WO claimed
EP-0763047-B1 NOVEL METHOD OF PRODUCING NUCLEOSIDES HOECHST AG (DE) 2002-01-23 EP claimed
US-5780607-A PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES HOFFMANN-LA ROCHE INC. (US) 1998-07-14 US claimed
WO-1997014709-A1 ANTISENSE OLIGOMERS F. HOFFMANN-LA ROCHE AG (CH) 1997-04-24 WO claimed
CN-1128269-A Oligoribonucleotides with amide backbone HOFFMANN LA ROCHE (CH) 1996-08-07 CN claimed
EP-0714907-A1 Oligoribonucleotides with amide backbone F. HOFFMANN-LA ROCHE AG (CH) 1996-06-05 EP claimed
WO-1994015622-A1 NUCLEOSIDE DERIVATIVES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS CAMBRIDGE NEUROSCIENCE (US) 1994-07-21 WO claimed