Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422581 | 0.82 | HTT (0.37) | ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL7151589 | 0.69 | — | — | |
| SCHEMBL1471268 | 0.64 | USP2 (0.38) | HPGDALDH1A1LMNACHKA | |
| SCHEMBL185803 | 0.61 | HPGD (0.39) | HPGDALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL1852700 | 0.61 | CHKA (0.38) | HPGDALDH1A1TSHRL3MBTL1MAPK1 | |
| SCHEMBL4638253 | 0.61 | HRH1 (0.35) | HPGDALDH1A1TSHRMAPK1CHKA | |
| SCHEMBL478677 | 0.60 | CYP1A2 (0.42) | HPGDALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL8026993 | 0.60 | CYP1A2 (0.42) | HPGDALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL21313021 | 0.59 | HPGD (0.41) | HPGDALDH1A1TSHRL3MBTL1MAPK1 | |
| SCHEMBL8540547 | 0.58 | CYP1A2 (0.46) | ALDH1A1TSHRLMNAMAPK1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759404-B2 | INHIBITING GAMMA-SECRETASE ACTIVITY; TREATING DISEASES ASSOCIATED WITH BETA-AMYLOID PRODUCTION, SUCH AS ALZHEIMER'S DISEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-07-06 | — | — | US | claimed |