Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638253 | 0.98 | HRH1 (0.35) | USP2SMN1; SMN2TDP1HTTMEN1 | |
| SCHEMBL17654278 | 0.93 | — | — | |
| SCHEMBL7380677 | 0.72 | — | — | |
| SCHEMBL1854770 | 0.71 | CYP1A2 (0.43) | TDP1HRH1CYP1A2 | |
| SCHEMBL6839409 | 0.64 | HPGD (0.32) | HPGDCHKAALDH1A1LMNA | |
| SCHEMBL1852700 | 0.63 | CHKA (0.38) | USP2SMN1; SMN2TDP1HTTMEN1 | |
| SCHEMBL185803 | 0.63 | HPGD (0.39) | SMN1; SMN2TDP1MEN1KMT2AHPGD | |
| SCHEMBL3432719 | 0.61 | NOTUM (0.40) | SMN1; SMN2HTTMEN1KMT2AMAPT | |
| SCHEMBL2992722 | 0.61 | CYP1A2 (0.42) | USP2SMN1; SMN2TDP1HTTHPGD | |
| SCHEMBL6751496 | 0.61 | ALDH1A1 (0.33) | USP2SMN1; SMN2TDP1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242116-B2 | Fused thiazole derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2012-08-14 | — | — | US | claimed |
| EP-2035436-B1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2011-05-25 | — | — | EP | claimed |
| US-20100137302-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-06-03 | — | — | US | claimed |
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | claimed |
| WO-2009071888-A1 | PYRROLOTHIAZOLES AS PI3-KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| WO-2009071890-A1 | TRICYCLIC KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| EP-2035436-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-18 | — | — | EP | claimed |
| WO-2008001076-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-01-03 | — | — | WO | claimed |
| US-9044413-B2 | Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants | SOLVAY USA INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-8907033-B2 | Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants | SOLVAY USA INC. (US) | 2014-12-09 | — | — | US | disclosed |
| EP-1322684-B1 | PROCESSES TO CONTROL THE RESIDUAL MONOMER LEVEL OF COPOLYMERS OF TERTIARY AMINO MONOMER WITH A VINYL-FUNCTIONAL MONOMER | SOLVAY USA INC (US) | 2014-05-07 | — | — | EP | disclosed |
| US-20140034076-A1 | POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS | RHODIA INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8580905-B2 | Polymers, compositions and methods of use for foams, laundry detergents, shower rinses and coagulants | RHODIA INC. (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2000029540-A1 | ULTRASONIC CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000029535-A1 | CLEANING PRODUCT WHICH USES SONIC OR ULTRASONIC WAVES | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000028874-A2 | ULTRASONIC CLEANING DEVICE | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-1999027058-A1 | DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS AND THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999027057-A1 | LIQUID DETERGENT COMPOSITIONS COMPRISING POLYMERIC SUDS ENHANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5869225-A | Processing method of silver halide photographic light sensitive material | KONICA CORPORATION (JP) | 1999-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137302-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | PI4KA, PDPK1, PIK3CA | USP2 3231/4885SMN1; SMN2 1521/4885TDP1 533/4885 |
| US-20140034076-A1 | POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS | DSG1, DSTN, CUTA | USP2 569/4885SMN1; SMN2 1228/4885TDP1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.