Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356852 | 0.84 | FFAR1 (0.62) | ESR1ESR2FFAR1PPARDPPARA | |
| SCHEMBL3021109 | 0.84 | FFAR1 (0.62) | ESR1ESR2FFAR1PPARDPPARA | |
| SCHEMBL3948386 | 0.84 | FFAR1 (0.62) | ESR1ESR2FFAR1PPARDPPARA | |
| SCHEMBL14061950 | 0.81 | CYP26A1 (0.67) | NQO2MTNR1AMTNR1BCYP26A1CYP19A1 | |
| SCHEMBL7693619 | 0.81 | ESR1 (0.54) | ESR1ESR2STSLMNAMAPT | |
| SCHEMBL7410004 | 0.80 | ESR1 (0.62) | ESR1ESR2NQO2MTNR1AMTNR1B | |
| SCHEMBL1567103 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BFFAR1PPARDHTR6 | |
| SCHEMBL8667329 | 0.79 | GRIN2B (0.43) | MAPTFFAR1PPARDHTR6PPARA | |
| SCHEMBL8669494 | 0.78 | MTNR1A (0.59) | NQO2MTNR1AMTNR1BFFAR1 | |
| SCHEMBL28048794 | 0.77 | ESR1 (0.59) | ESR1ESR2NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414809-A1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | Bayer Corporation (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011842-A1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |