Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668520 | 0.86 | FFAR1 (0.55) | GRIN2BFFAR1PPARDPPARA | |
| SCHEMBL6839634 | 0.79 | ESR1 (0.57) | FFAR1MAPTHTR6PPARDPPARA | |
| SCHEMBL8702101 | 0.77 | GRIN2B (0.42) | GRIN2BHSP90AA1PNMT | |
| SCHEMBL9014699 | 0.75 | PNMT (0.40) | GRIN2BHSP90AA1HTR6PNMT | |
| SCHEMBL1567103 | 0.74 | MTNR1A (0.56) | FFAR1HTR6L3MBTL1PPARD | |
| SCHEMBL8667327 | 0.74 | PNMT (0.50) | HSP90AA1ALDH1A1MAPTPNMT | |
| SCHEMBL8669494 | 0.73 | MTNR1A (0.59) | FFAR1CYP1A2 | |
| SCHEMBL2244560 | 0.71 | LAP3 (0.48) | GRIN2BHSP90AA1ALDH1A1MAPTPNMT | |
| SCHEMBL8548146 | 0.71 | PNMT (0.44) | GRIN2BHSP90AA1ALDH1A1MAPTPNMT | |
| SCHEMBL7214649 | 0.71 | PNMT (0.48) | GRIN2BHSP90AA1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1998005651-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYL QUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |