Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 2/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840047 | 1.00 | NPC1 (0.56) | NPC1RAB9AMYCMAXPIK3CG | |
| SCHEMBL6839936 | 0.90 | PIK3CG (0.51) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6839935 | 0.90 | PIK3CG (0.51) | PIK3CGCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL6174177 | 0.88 | PIK3CG (0.55) | RAB9AMYCMAXPIK3CGCSNK2A2 | |
| SCHEMBL6186331 | 0.88 | PIK3CG (0.59) | NPC1RAB9AMYCPIK3CGCSNK2A2 | |
| SCHEMBL6186328 | 0.88 | PIK3CG (0.59) | NPC1RAB9AMYCPIK3CGCSNK2A2 | |
| SCHEMBL6835905 | 0.86 | NAT1 (0.55) | RAB9AMYCMAXPIK3CGCSNK2A2 | |
| SCHEMBL6835907 | 0.86 | NAT1 (0.55) | RAB9AMYCMAXPIK3CGCSNK2A2 | |
| SCHEMBL6188174 | 0.86 | PIK3CG (0.59) | MYCMAXPIK3CGCSNK2A2CLK1 | |
| SCHEMBL6188170 | 0.86 | PIK3CG (0.59) | MYCMAXPIK3CGCSNK2A2CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138199-A1 | Benzoxazines and derivatives thereof as therapeutic agents | XDH, TBXA2R, TBXAS1 | NPC1 4011/4885RAB9A 1076/4885MYC 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.