Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054065 | 0.81 | ADRA2C (0.46) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL2373415 | 0.79 | ADRA2C (0.45) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL9201789 | 0.79 | KDM4E (0.56) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL8287058 | 0.79 | KDM4E (0.56) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL15450086 | 0.79 | LMNA (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL23221180 | 0.79 | KDM4E (0.56) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL3245155 | 0.79 | KDM4E (0.56) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL13458547 | 0.79 | LMNA (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL10189483 | 0.77 | KDM4E (0.54) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL11789068 | 0.77 | KDM4E (0.54) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214232-A1 | Generation of skeletal diversity within a combinatorial library | HOWARD HUGHES MEDICAL INSTITUTE | 2004-10-28 | — | — | US | disclosed |