Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951317 | 0.82 | KIF11 (0.55) | KIF11KMT2ARAB9A | |
| SCHEMBL10977541 | 0.82 | KIF11 (0.55) | KIF11KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL3610046 | 0.80 | KIF11 (0.53) | KIF11KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL3610043 | 0.80 | KIF11 (0.53) | KIF11KMT2ARAB9A | |
| SCHEMBL1693107 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL29627252 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL19699200 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL2058766 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E | |
| Hydrochloric Acid SCHEMBL23824596 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E | |
| Hydrochloric Acid SCHEMBL5568685 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765109-B1 | FORMATION OF ENANTIOSELECTIVE MATERIAL; REACTING ARYL THIOL AND PROTECTED SERINE DERIVATIVE | ROCHE COLORADO CORPORATION | 2004-07-20 | — | — | US | disclosed |
| EP-0968997-B1 | Process for S-aryl-L-cysteine and derivatives | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1236715-A2 | Process for S-Aryl cysteine | F. HOFFMANN-LA ROCHE AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| US-6229041-B1 | COUPLING CYSTEINE WITH COPPER OR COPPER OXIDE TO GENERATE METAL-AMINO COMPLEX, THEN CONTACTING WITH ARYL-HALIDE TO PRODUCE 3-ARYL-CYSTEINE; XENOBIOTIC METABOLIC PATHWAYS; TARGETTING HIV VIRUS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-05-08 | — | — | US | disclosed |
| EP-0968997-A2 | Process for S-aryl-L-cysteine and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-05 | — | — | EP | disclosed |