Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.50 |
| ▸ | PGR | P06401 | 8/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.50 |
| ▸ | SHBG | P04278 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974319 | 1.00 | AR (0.50) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL5974247 | 0.86 | ESR1 (0.49) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL6838182 | 0.86 | AR (0.49) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL14275154 | 0.86 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL4362587 | 0.86 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL565277 | 0.86 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| Mibolerone SCHEMBL10603681 | 0.86 | AR (0.67) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL24476271 | 0.85 | PGR (0.54) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL5974963 | 0.85 | PGR (0.54) | ARPGRNR3C2SHBGALDH1A1 | |
| SCHEMBL23822244 | 0.85 | PGR (0.54) | ARPGRNR3C2SHBGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043972-A1 | 3-Methylene steroid derivatives | AKZO NOBEL N.V. (NL) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043972-A1 | 3-Methylene steroid derivatives | HSD17B11, NR5A1, CYP17A1 | AR 29/4885PGR 26/4885NR3C2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.