Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064122 | 0.85 | TYR (0.52) | TAAR1TYRGAATSHRHTT | |
| SCHEMBL6842020 | 0.85 | TAAR1 (0.53) | TAAR1TYRHTR2AHTR2CHTR2B | |
| SCHEMBL9485194 | 0.74 | TYR (0.57) | TAAR1TYRTSHRKMT2A | |
| SCHEMBL6841238 | 0.74 | TYR (0.42) | TAAR1TYRHTR2AHTR2BSLC6A2 | |
| SCHEMBL2107 | 0.72 | TAAR1 (1.00) | TAAR1HTR2AAOC3CHRNB2CHRNA4 | |
| SCHEMBL238388 | 0.72 | TAAR1 (1.00) | TAAR1HTR2AAOC3CHRNB2CHRNA4 | |
| SCHEMBL240503 | 0.72 | TAAR1 (1.00) | TAAR1HTR2AAOC3CHRNB2CHRNA4 | |
| SCHEMBL10492513 | 0.71 | TYR (0.43) | TAAR1TYRGAATSHRHTT | |
| SCHEMBL10386818 | 0.71 | TAAR1 (0.52) | TAAR1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL30717251 | 0.71 | TAAR1 (0.52) | TAAR1HTR2AHTR2CHTR2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |