Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841237 | 0.85 | TAAR1 (0.55) | TAAR1TYRHTR2ASLC6A4HTR2C | |
| SCHEMBL6841424 | 0.78 | SLC6A4 (0.57) | TAAR1SLC6A4NISCHIDO1TDO2 | |
| Hydrochloric Acid SCHEMBL6836833 | 0.76 | SLC6A4 (0.56) | TAAR1SLC6A4NISCHIDO1TDO2 | |
| SCHEMBL6842021 | 0.75 | SLC6A4 (0.47) | TYRHTR2ASLC6A4 | |
| SCHEMBL6841273 | 0.75 | TAAR1 (0.46) | TAAR1HTR2ASLC6A4HTR2CHTR2B | |
| SCHEMBL6841213 | 0.74 | TAAR1 (0.46) | TAAR1HTR2ASLC6A4HTR2CHTR2B | |
| SCHEMBL9485194 | 0.73 | TYR (0.57) | TAAR1TYR | |
| SCHEMBL1431673 | 0.72 | NISCH (0.58) | TAAR1HTR2ASLC6A4HTR2CHTR2B | |
| SCHEMBL240503 | 0.71 | TAAR1 (1.00) | TAAR1HTR2AAOC3CHRNB2CHRNA4 | |
| SCHEMBL2107 | 0.71 | TAAR1 (1.00) | TAAR1HTR2AAOC3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |