Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.63 |
| ▸ | HTR3A | P46098 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841408 | 0.97 | HTR4 (0.66) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6840589 | 0.91 | HTR4 (0.71) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6843006 | 0.90 | HTR4 (0.75) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL29470996 | 0.88 | HTR4 (0.75) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL8285631 | 0.88 | HTR4 (0.75) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6841386 | 0.88 | HTR4 (0.68) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6843077 | 0.88 | HTR4 (0.77) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6840598 | 0.87 | HTR4 (0.73) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| Hydrochloric Acid SCHEMBL6841284 | 0.87 | HTR4 (0.76) | HTR4DRD4CYP1A2CYP3A4ADRA2A | |
| SCHEMBL6836059 | 0.87 | HTR4 (0.70) | HTR4DRD4CYP1A2CYP3A4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087622-A1 | Benzamide derivative and medicament containing the same | KATO HIDEO (JP) | 2004-05-06 | — | — | US | disclosed |
| US-6638951-B1 | Medicament has excellent enhancing action on gastrointestinal tract motility, and is orally available with reduced side effects, the agent for therapeutic treatment of digestive diseases, an agent for improving function of gastrointestinal | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1149832-B1 | BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU PHARMACEUTICAL (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1149832-A1 | BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087622-A1 | Benzamide derivative and medicament containing the same | SLC10A2, FABP2, HDAC6 | HTR4 598/4885DRD4 1433/4885CYP1A2 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.