SCHEMBL6841491

SCHEMBL6841491

CCCCCCCCCC[Si](C)(O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
DNM1 Q05193 4/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6841032 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL3503473 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL6841439 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL968833 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL6841495 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL968566 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL1143377 0.97
SCHEMBL6841033 0.88
SCHEMBL13254747 0.87 HDAC3 (0.41)
SCHEMBL4521495 0.86 ALDH1A1 (0.56) TSHRALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6764807-B2 LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-07-20 US disclosed
US-20020086235-A1 Lithography EASTMAN KODAK COMPANY 2002-07-04 US disclosed
US-6399271-B1 HYDROXY CONTAINING COMPOUND WITH AFFINITY FOR INK, AND TITANIUM OR SILICON CONTAINING COMPOUND WITH DIFFERENT AFFINITY FOR INK KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
EP-1021301-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 2000-07-26 EP disclosed
WO-1999014048-A1 PLANOGRAPHIC PRINTING KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 1999-03-25 WO disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed