SCHEMBL968833

SCHEMBL968833

CCCCCCCCCCCCCCCCCC[Si](C)(O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
DNM1 Q05193 4/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6841032 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL3503473 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL6841439 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL6841495 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL6841491 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL968566 1.00 TSHR (0.47) TSHRTHRBLMNAALDH1A1HSD17B10
SCHEMBL1143377 0.97
SCHEMBL6841033 0.88
SCHEMBL13254747 0.87 HDAC3 (0.41)
SCHEMBL4521495 0.86 ALDH1A1 (0.56) TSHRALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379634-B1 RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN & CIE (FR) 2016-04-20 EP disclosed
CN-101855287-B Rubber composition for a tire comprising a hydroxysilane covering agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-01-20 CN disclosed
US-8623937-B2 Rubber compound containing a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-07 US disclosed
US-8623937-B2 Rubber compound containing a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-07 US disclosed
US-8623937-B2 Rubber compound containing a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2014-01-07 US disclosed
CN-102300917-B Rubber Compound Containing A Blocked Mercaptosilane Coupling Agent MICHELIN SOC TECH 2013-09-04 CN disclosed
CN-102300917-A Rubber Compound Containing A Blocked Mercaptosilane Coupling Agent 2011-12-28 CN disclosed
US-20110294915-A1 RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-12-01 US disclosed
US-20110294915-A1 RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-12-01 US disclosed
EP-2379634-A1 RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT Société de Technologie MICHELIN (FR) 2011-10-26 EP disclosed
CN-101855287-A Rubber composition for a tire comprising a hydroxysilane covering agent MICHELIN SOC TECH 2010-10-06 CN disclosed
EP-2212379-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT Société de Technologie MICHELIN (FR) 2010-08-04 EP disclosed
WO-2010072683-A1 RUBBER COMPOUND CONTAINING A BLOCKED MERCAPTOSILANE COUPLING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2010-07-01 WO disclosed
WO-2009062733-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2009-05-22 WO disclosed
US-6764807-B2 LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-07-20 US disclosed
US-20020086235-A1 Lithography EASTMAN KODAK COMPANY 2002-07-04 US disclosed
US-6399271-B1 HYDROXY CONTAINING COMPOUND WITH AFFINITY FOR INK, AND TITANIUM OR SILICON CONTAINING COMPOUND WITH DIFFERENT AFFINITY FOR INK KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
EP-1021301-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 2000-07-26 EP disclosed
WO-1999014048-A1 PLANOGRAPHIC PRINTING KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 1999-03-25 WO disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed