SCHEMBL6841533

SCHEMBL6841533

CCc1ccccc1CC.OP(O)(O)=S.OP(O)(O)=S

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
GABRB2 P47870 3/20 0.50
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 2/20 0.42
MGLL Q99685 1/20 0.40
NPSR1 Q6W5P4 2/20 0.38
ACP3 P15309 1/20 0.38
TP53 P04637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27335695 1.00 GABRA1 (0.50) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL730990 0.97 GABRA1 (0.48) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL10988293 0.90 GABRA1 (0.46) GABRA1GABRB2MAPTALDH1A1GAA
Phosphoric Acid SCHEMBL28176644 0.86 GABRA1 (0.52) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL27633384 0.84 GABRA1 (0.41) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL27509930 0.84 GABRA1 (0.41) GABRA1GABRB2MAPTALDH1A1GAA
Hydrogen Peroxide SCHEMBL11205186 0.83 GABRA1 (0.60) GABRA1GABRB2MAPTALDH1A1GAA
Hydrogen Peroxide SCHEMBL10890655 0.83 GABRA1 (0.60) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL25425763 0.83 GABRA1 (0.58) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL29390847 0.83 GABRA1 (0.58) GABRA1GABRB2MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040224859-A1 low noise and high lubricity; mixture of diurea compounds and zinc or molybdenum dithiophosphates or dithiocarbonates; synergistic effects of such S-P type additives with the urea thickening agents SHELL OIL COMPANY 2004-11-11 US disclosed