SCHEMBL730990

SCHEMBL730990

CCc1ccccc1CC.OP(O)(O)=S.OP(O)(O)=S.[Zn]

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.48
GABRB2 P47870 3/20 0.48
MAPT P10636 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 2/20 0.41
MGLL Q99685 1/20 0.39
NPSR1 Q6W5P4 2/20 0.36
ACP3 P15309 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.36
TP53 P04637 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27335695 0.97 GABRA1 (0.50) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL6841533 0.97 GABRA1 (0.50) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL10988293 0.88 GABRA1 (0.46) GABRA1GABRB2MAPTALDH1A1GAA
Phosphoric Acid SCHEMBL28176644 0.84 GABRA1 (0.52) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL27633384 0.82 GABRA1 (0.41) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL27509930 0.82 GABRA1 (0.41) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL940137 0.81 LIPG (0.38) GABRA1GABRB2TSHR
Hydrogen Peroxide SCHEMBL11205186 0.81 GABRA1 (0.60) GABRA1GABRB2MAPTALDH1A1GAA
Hydrogen Peroxide SCHEMBL10890655 0.81 GABRA1 (0.60) GABRA1GABRB2MAPTALDH1A1GAA
SCHEMBL25425763 0.81 GABRA1 (0.58) GABRA1GABRB2MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1570034-B1 UREA GREASE COMPOSITION SHELL INT RESEARCH (NL) 2016-02-17 EP disclosed
EP-1639063-B1 Use of a Grease Composition SHELL INT RESEARCH (NL) 2014-06-25 EP disclosed
EP-1443061-B2 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-10-31 EP disclosed
EP-2287210-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-07-18 EP disclosed
EP-1831338-B1 UREA-BASED LUBRICATING GREASE COMPOSITION SHELL INT RESEARCH (NL) 2012-06-13 EP disclosed
US-8138130-B2 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE COMPANY LLC (US) 2012-03-20 US disclosed
EP-1707616-B1 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE CO (US) 2011-06-22 EP disclosed
EP-2287210-A2 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2011-02-23 EP disclosed
US-7867956-B2 Urea-based lubricating grease composition SHELL OIL COMPANY (US) 2011-01-11 US disclosed
EP-1857474-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2010-09-22 EP disclosed
WO-2004113481-A1 GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-12-29 WO disclosed
US-20040224859-A1 low noise and high lubricity; mixture of diurea compounds and zinc or molybdenum dithiophosphates or dithiocarbonates; synergistic effects of such S-P type additives with the urea thickening agents SHELL OIL COMPANY 2004-11-11 US disclosed
US-20040152817-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE COMPANY LLC 2004-08-05 US disclosed
EP-1443061-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2004-08-04 EP disclosed
WO-2004053032-A1 UREA GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2004-06-24 WO disclosed
US-5912212-A OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS NIPPON OIL CO., LTD. (JP) 1999-06-15 US disclosed
EP-0896050-A1 Lubricating oil composition comprising a specific base oil and an oxidation inhibitor NIPPON OIL CO., LTD. (JP) 1999-02-10 EP disclosed
EP-0781834-A2 Lubricating oil composition NIPPON OIL CO. LTD. (JP) 1997-07-02 EP disclosed
US-4163729-A LUBRICATING OIL CHEVRON RESEARCH COMPANY (US) 1979-08-07 US disclosed
US-4089790-A Synergistic combinations of hydrated potassium borate, antiwear agents, and organic sulfide antioxidants CHEVRON RESEARCH COMPANY (US) 1978-05-16 US disclosed