Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841273 | 0.83 | TAAR1 (0.46) | HTR2ATAAR1HTR2CHTR2BSLC6A2 | |
| SCHEMBL6842241 | 0.82 | TAAR1 (0.46) | HTR2ATAAR1HTR2CHTR2BTYR | |
| SCHEMBL6843795 | 0.80 | HTR2A (0.44) | HTR2ATAAR1HTR2CHTR2BSLC6A2 | |
| SCHEMBL12378777 | 0.77 | TAAR1 (0.60) | HTR2ATAAR1ALOX5PYCR1MAOA | |
| SCHEMBL175157 | 0.77 | TAAR1 (0.60) | HTR2ATAAR1ALOX5PYCR1MAOA | |
| SCHEMBL20425554 | 0.77 | TAAR1 (0.60) | HTR2ATAAR1ALOX5PYCR1MAOA | |
| SCHEMBL6841424 | 0.76 | SLC6A4 (0.57) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6841427 | 0.75 | TAAR1 (0.36) | HTR2ATAAR1HTR2CHTR2BSLC6A4 | |
| Hydrochloric Acid SCHEMBL5877710 | 0.75 | TAAR1 (0.58) | HTR2ATAAR1ALOX5PYCR1MAOA | |
| Hydrochloric Acid SCHEMBL5877704 | 0.75 | TAAR1 (0.58) | HTR2ATAAR1ALOX5PYCR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |