Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841573 | 0.83 | HTR2A (0.50) | TAAR1HTR2BHTR2AHTR2CSLC6A4 | |
| SCHEMBL6841424 | 0.82 | SLC6A4 (0.57) | TAAR1SLC6A4CYP3A4SLC6A3SLC6A2 | |
| SCHEMBL6841213 | 0.82 | TAAR1 (0.46) | TAAR1ADRB2HTR2BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6836833 | 0.81 | SLC6A4 (0.56) | TAAR1SLC6A4CYP3A4SLC6A3SLC6A2 | |
| SCHEMBL6843795 | 0.80 | HTR2A (0.44) | TAAR1HTR2BHTR2AHTR2CCYP2C9 | |
| SCHEMBL1032332 | 0.77 | TAAR1 (0.60) | TAAR1CHRNA7ADRB2C3AR1TSHR | |
| SCHEMBL21286089 | 0.77 | TAAR1 (0.60) | TAAR1CHRNA7ADRB2C3AR1TSHR | |
| SCHEMBL21286098 | 0.77 | TAAR1 (0.60) | TAAR1CHRNA7ADRB2C3AR1TSHR | |
| SCHEMBL7914810 | 0.77 | ADRB2 (0.47) | CHRNA7ADRB2HTR2BHTR2AC3AR1 | |
| SCHEMBL27370497 | 0.77 | ADRB2 (0.42) | ADRB2HTR2BHTR2AC3AR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |