Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841273 | 0.80 | TAAR1 (0.46) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| SCHEMBL6841573 | 0.80 | HTR2A (0.50) | HTR2AHTR2CHTR2BTAAR1SLC6A4 | |
| SCHEMBL1989112 | 0.79 | TAAR1 (0.56) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| SCHEMBL4014153 | 0.79 | TAAR1 (0.56) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| SCHEMBL6183991 | 0.79 | TAAR1 (0.56) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL5877324 | 0.77 | TAAR1 (0.54) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| SCHEMBL6843796 | 0.75 | CYP2D6 (0.54) | HTR2AALDH1A1SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL336166 | 0.73 | TAAR1 (0.48) | HTR2AHTR2CHTR2BALDH1A1TAAR1 | |
| SCHEMBL6841424 | 0.73 | SLC6A4 (0.57) | TAAR1SLC6A4SLC6A2CYP2D6CYP3A4 | |
| SCHEMBL156425 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | claimed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |