SCHEMBL6841673

SCHEMBL6841673

C=CC[Si](O)(O)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
CYP2C19 P33261 1/20 0.34
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
MMP9 P14780 2/20 0.33
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
AKT1 P31749 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MMP1 P03956 1/20 0.31
MMP12 P39900 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1566054 0.82 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL15302725 0.82 ALDH1A1 (0.34) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL27912803 0.79 HTT (0.33) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL2290391 0.78 NR1H2 (0.42) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL723613 0.78 ALDH1A1 (0.38) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL536223 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL296966 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL2292460 0.75 NR1H2 (0.33) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL7118374 0.74 ALDH1A1 (0.35) ALDH1A1TSHRCYP2C19NR1H2NR1H3
SCHEMBL27571897 0.74 HTT (0.34) ALDH1A1TSHRHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594175-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1997-06-18 EP claimed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
US-6764807-B2 LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-07-20 US disclosed
US-20020086235-A1 Lithography EASTMAN KODAK COMPANY 2002-07-04 US disclosed
US-6399271-B1 HYDROXY CONTAINING COMPOUND WITH AFFINITY FOR INK, AND TITANIUM OR SILICON CONTAINING COMPOUND WITH DIFFERENT AFFINITY FOR INK KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
EP-1021301-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 2000-07-26 EP disclosed
WO-1999014048-A1 PLANOGRAPHIC PRINTING KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 1999-03-25 WO disclosed
EP-0594175-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1997-06-18 EP disclosed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US disclosed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 ALDH1A1 2073/4885TSHR 4702/4885CYP2C19 4829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.