SCHEMBL536223

SCHEMBL536223

C=CC[Si](CC=C)(CC=C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.33
CYP2C19 P33261 1/20 0.32
IDH1 O75874 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31
AKT1 P31749 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7118374 0.98 ALDH1A1 (0.35) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL14954643 0.87 NR1H2 (0.33) ALDH1A1TSHRL3MBTL1NR1H2NR1H3
SCHEMBL723613 0.82 ALDH1A1 (0.38) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL296966 0.80 ALDH1A1 (0.36) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL8084333 0.79 KCNH2 (0.34) ALDH1A1TSHRHTT
SCHEMBL9559606 0.79
SCHEMBL14764651 0.78 ADH1B (0.39) ALDH1A1CYP2C19IDH1HPGD
SCHEMBL16477652 0.76 NR1H2 (0.33) NR1H2NR1H3
SCHEMBL9862805 0.76 NR1H2 (0.37) ALDH1A1TSHRL3MBTL1CYP2C19IDH1
SCHEMBL1493187 0.76 ALDH1A1 (0.33) ALDH1A1TSHRL3MBTL1CYP2C19IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163346-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2025-05-22 US claimed
US-12215299-B2 Treatment compositions THE PROCTER & GAMBLE COMPANY (US) 2025-02-04 US claimed
CN-118620630-A Modified coal gangue, preparation method thereof and soil improvement 国家能源集团新疆能源有限责任公司 2024-09-10 CN claimed
CN-117986579-A Photosensitive polyimide resin composition, preparation method and application thereof, and photosensitive polyimide precursor micromolecule 中国科学院兰州化学物理研究所 2024-05-07 CN claimed
CN-114133499-B Micro acrylic capsule resin and preparation method and application thereof 上海金力泰化工股份有限公司 2024-04-23 CN claimed
CN-115477758-B Fluorine-containing defoaming agent and preparation method thereof 江门市华熊新材料有限公司 2023-10-10 CN claimed
US-20230242842-A1 TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2023-08-03 US claimed
CN-116375980-A Halogen-free or low-halogen anti-corrosion epoxy resin prepared by epoxidation of olefin-based anhydrous peroxy acid, and preparation method and application thereof 国科广化(南雄)新材料研究院有限公司 2023-07-04 CN claimed
US-11643618-B2 Treatment compositions THE PROCTER & GAMBLE COMPANY (US) 2023-05-09 US claimed
CN-115477758-A Fluorine-containing defoaming agent and preparation method thereof 江门市华熊新材料有限公司 2022-12-16 CN claimed
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US claimed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US claimed
CN-101331189-A Fluoropolymer curing co-agent compositions 3M INNOVATIVE PROPERTIES CO (US) 2008-12-24 CN claimed
EP-1963427-A1 FLUOROPOLYMER CURING CO-AGENT COMPOSITIONS 3M Innovative Properties Company (US) 2008-09-03 EP claimed
US-7388054-B2 Fluoropolymer curing co-agent compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-06-17 US claimed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO claimed
WO-2007075261-A1 FLUOROPOLYMER CURING CO-AGENT COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO claimed
US-20070149714-A1 FLUOROPOLYMER CURING CO-AGENT COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2007-06-28 US claimed
EP-1232163-A1 PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES ALBEMARLE CORPORATION (US) 2002-08-21 EP claimed
WO-2001038333-A1 PRODUCTION OF DISUBSTITUTED PENTAFULVENS VIA LITHIATED SILYL-(HALO)ARENE INTERMEDIATES ALBEMARLE CORPORATION (US) 2001-05-31 WO claimed