Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.65 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842196 | 1.00 | TYR (0.65) | TYRSLC28A3TSHR | |
| Picein SCHEMBL467773 | 0.99 | TYR (0.68) | TYRSLC28A3TSHR | |
| Picein SCHEMBL8977498 | 0.99 | TYR (0.68) | TYRSLC28A3TSHR | |
| Picein SCHEMBL47006 | 0.99 | TYR (0.68) | TYRSLC28A3TSHR | |
| Picein SCHEMBL467772 | 0.99 | TYR (0.68) | TYRSLC28A3TSHR | |
| SCHEMBL10048492 | 0.87 | TYR (0.50) | TYRSLC28A3TSHR | |
| SCHEMBL24198665 | 0.87 | TYR (0.67) | TYR | |
| SCHEMBL29129002 | 0.86 | TYR (0.69) | TYR | |
| SCHEMBL24198671 | 0.86 | TYR (0.69) | TYR | |
| SCHEMBL467724 | 0.86 | TYR (0.69) | TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6764829-B2 | DETECTING PARASITES USING CHROMOGENIC SUBSTRATES; OBTAIN SAMPLE, INCUBATE WITH CHROMGENIC SUBSTRATE, DETECT FORMATION OF CHROMOPHORE PRODUCT | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2004-07-20 | — | — | US | disclosed |
| US-20020132263-A1 | Enzyme detection/assay method and substrates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-19 | — | — | US | disclosed |
| US-6379911-B2 | ANALYZING NUCLEOSIDE HYDROLASES; DETECTING PARASITES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2002-04-30 | — | — | US | disclosed |
| US-20010019823-A1 | ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-09-06 | — | — | US | disclosed |
| WO-1997031008-A1 | ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES | INDUSTRIAL RESEARCH LIMITED (NZ) | 1997-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019823-A1 | ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES | PNP, TREH, XDH | TYR 264/4885SLC28A3 3540/4885TSHR 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.